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Jeffrey G McDonald Selected Research

25-hydroxycholesterol

10/202325-Hydroxycholesterol exacerbates vascular leak during acute lung injury.
1/2023Macrophage-Derived 25-Hydroxycholesterol Promotes Vascular Inflammation, Atherogenesis, and Lesion Remodeling.
5/2022Association of demographic and health characteristics with circulating oxysterol concentrations.
11/2017Oxysterol Restraint of Cholesterol Synthesis Prevents AIM2 Inflammasome Activation.
8/2014Inflammation. 25-Hydroxycholesterol suppresses interleukin-1-driven inflammation downstream of type I interferon.

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Jeffrey G McDonald Research Topics

Disease

14Neoplasms (Cancer)
01/2023 - 10/2009
9Inflammation (Inflammations)
03/2024 - 09/2012
5Breast Neoplasms (Breast Cancer)
01/2022 - 11/2013
3Pneumonia (Pneumonitis)
12/2023 - 01/2020
3Obesity
07/2023 - 08/2014
3Infections
01/2023 - 01/2020
3Atherosclerosis
01/2023 - 01/2018
3Hepatocellular Carcinoma (Hepatoma)
01/2022 - 11/2017
2Weight Loss (Weight Reduction)
12/2023 - 11/2019
2Glioma (Gliomas)
01/2023 - 01/2019
2Adenoma (Adenomas)
05/2022 - 01/2021
2Fatty Liver
01/2022 - 08/2014
2Disease Progression
11/2021 - 08/2017
2Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 01/2020
2Bacterial Infections (Bacterial Infection)
01/2020 - 11/2017
2Renal Cell Carcinoma (Grawitz Tumor)
12/2019 - 08/2017
2Insulin Resistance
11/2019 - 08/2015
2Type 2 Diabetes Mellitus (MODY)
01/2018 - 08/2014
1Genetic Predisposition to Disease (Genetic Predisposition)
03/2024
1Pulmonary Arterial Hypertension
03/2024
1Vulvar Lichen Sclerosus
02/2024
1Metabolic Diseases (Metabolic Disease)
01/2024
1Liver Diseases (Liver Disease)
01/2024
1COVID-19
12/2023
1Acute Lung Injury
10/2023
1Lung Injury
10/2023
1Neoplasm Metastasis (Metastasis)
01/2023
1Left Ventricular Dysfunction
01/2023
1Heart Diseases (Heart Disease)
01/2023
1Premature Birth (Birth, Premature)
10/2022
1Smith-Lemli-Opitz Syndrome
01/2022
1Necrosis
01/2022
1Liver Neoplasms (Liver Cancer)
01/2022
1Lung Neoplasms (Lung Cancer)
01/2022
1Atherosclerotic Plaque (Atheroma)
11/2021
1Polyps
01/2021
1Spinocerebellar Ataxias (Spinocerebellar Ataxia)
12/2020
1Cerebellar Ataxia (Dysmetria)
12/2020
1Pain (Aches)
11/2020
1Hyperalgesia
11/2020

Drug/Important Bio-Agent (IBA)

18CholesterolIBA
01/2023 - 09/2007
10LipidsIBA
01/2024 - 03/2015
8OxysterolsIBA
03/2024 - 01/2017
6SterolsIBA
03/2024 - 09/2007
525-hydroxycholesterolIBA
10/2023 - 08/2014
5Proteins (Proteins, Gene)FDA Link
01/2023 - 11/2017
4Liver X ReceptorsIBA
10/2023 - 01/2018
427-hydroxycholesterolIBA
05/2022 - 11/2013
4oxidized low density lipoproteinIBA
01/2022 - 11/2017
4EnzymesIBA
11/2021 - 11/2013
4LigandsIBA
11/2020 - 11/2013
4Glucose (Dextrose)FDA LinkGeneric
11/2019 - 10/2009
3CytokinesIBA
12/2023 - 01/2017
3Docosahexaenoic AcidsIBA
01/2022 - 11/2017
3LDL Lipoproteins (beta Lipoproteins)IBA
01/2022 - 11/2017
3InflammasomesIBA
11/2021 - 11/2017
2ProgesteroneFDA LinkGeneric
02/2024 - 10/2022
2Insulin (Novolin)FDA Link
01/2024 - 11/2019
2lanosterol synthaseIBA
01/2023 - 01/2019
2Triglycerides (Triacylglycerol)IBA
01/2023 - 08/2017
224,25-epoxycholesterolIBA
01/2023 - 01/2019
2Fatty Acids (Saturated Fatty Acids)IBA
01/2022 - 01/2018
2DesmosterolIBA
11/2021 - 01/2018
2Selective Estrogen Receptor Modulators (SERM)IBA
01/2021 - 08/2014
2CalciumIBA
01/2021 - 11/2020
2Transcription Factors (Transcription Factor)IBA
11/2017 - 09/2007
2Interferon Type IIBA
11/2017 - 08/2014
2Biomarkers (Surrogate Marker)IBA
08/2017 - 03/2015
2Estrogens (Estrogen)FDA Link
08/2014 - 11/2013
2SteroidsIBA
08/2014 - 12/2011
1Bile Acids and Salts (Bile Acids)IBA
03/2024
1EstroneFDA Link
02/2024
1Hormones (Hormone)IBA
02/2024
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2024
1Chemotactic FactorsIBA
12/2023
1NIBR189IBA
12/2023
1Therapeutic UsesIBA
12/2023
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
12/2023
1Cytochrome P450 Family 7IBA
12/2023
1AlbuminsIBA
12/2023
1Indicators and Reagents (Reagents)IBA
12/2023
1Anti-Bacterial Agents (Antibiotics)IBA
07/2023
1Dynamins (Dynamin)IBA
01/2023
1erucylphosphocholineIBA
01/2023
1Histones (Histone)IBA
01/2022
1Lipoproteins (Lipoprotein)IBA
01/2022
1Lysine (L-Lysine)FDA Link
01/2022
1Phospholipid Hydroperoxide Glutathione PeroxidaseIBA
01/2022
1TrioleinIBA
01/2022
1Glutamic Acid (Glutamate)FDA Link
01/2022
17-dehydrocholesterol reductaseIBA
01/2022
1ApolipoproteinsIBA
01/2022
1NF-kappa B (NF-kB)IBA
01/2022
1InterferonsIBA
11/2021
1Vitamin DFDA LinkGeneric
01/2021
1A-factor (Streptomyces)IBA
12/2020
1Narcotics (Narcotic Analgesics)IBA
11/2020

Therapy/Procedure

1Chemoprevention
05/2022
1Vascular Access Devices (Arterial Line)
01/2022
1Spinal Injections
11/2020